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Cannabis: debated schizophrenia link

Nature volume 527, page 305 (2015)Cite this article

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In our view, Matthew Hill's arguments against a causal link between cannabis use and schizophrenia fail to clinch this debate (Nature 525, S14; 2015).

His contention that the increased societal use of cannabis over time is not reflected in increased rates of schizophrenia has been tested only once to our knowledge — and that study came to the opposite conclusion (J. Boydell et al. Psychol. Med. 36, 1441–1446; 2006). In multifactorial conditions such as schizophrenia, an increase in one risk factor is not necessarily balanced by a decrease in another. Deaths from cardiac disease are declining in many countries despite increased obesity, but that does not mean that obesity is unrelated to cardiac disease.

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Authors and Affiliations

  1. University of New South Wales, Australia

    Matthew Large

  2. Kings College London, UK

    Marta Di Forti & Robin Murray

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  1. Matthew Large
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  2. Marta Di Forti
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  3. Robin Murray
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Correspondence to Matthew Large.

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Large, M., Di Forti, M. & Murray, R. Cannabis: debated schizophrenia link. Nature 527, 305 (2015). https://doi.org/10.1038/527305e

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