Induced pluripotent stem cells were supposed to herald a medical revolution. But ten years after their discovery, they are transforming biological research instead.
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References
Takahashi, K. & Yamanaka, S. Cell 126, 663–676 (2006).
Okita, K., Ichisaka, T. & Yamanaka, S. Nature 448, 313–317 (2007).
Wernig, M. et al. Nature 448, 318–324 (2007).
Maherali, N. et al. Cell Stem Cell 1, 55–70 (2007).
Takahashi, K. et al. Cell 131, 861–872 (2007).
Yu, J. et al. Science 318, 1917–1920 (2007).
Nakagawa, M. et al. Nature Biotechnol. 26, 101–106 (2007).
Kim, K. et al. Nature 467, 285–290 (2010).
Paquet, D. et al. Nature 533, 125–129 (2016).
Qian, X. et al. Cell 165, 1238–1254 (2016).
Tucker, B. A. et al. J. Stem Cell Res. Ther. 3, 161 (2014).
HD iPSC Consortium Cell Stem Cell 11, 264–278 (2012).
Lee, G. et al. Nature Biotechnol. 30, 1244–1248 (2012).
Cao, L. et al. Sci. Transl. Med. 8, 335ra56 (2016).
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Scudellari, M. How iPS cells changed the world. Nature 534, 310–312 (2016). https://doi.org/10.1038/534310a
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DOI: https://doi.org/10.1038/534310a
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