Until this obstacle is overcome, the technology is unlikely to succeed in the wild.
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References
Hammond, A. et al. Nature Biotechnol. 34, 78–83 (2016).
Unckless, R. L., Clark, A. G. & Messer, P. W. Genetics http://dx.doi.org/10.1534/genetics.116.197285 (2016).
Miles, A. et al. Preprint at bioRxiv http://dx.doi.org/10.1101/096289 (2016).
Drury, D., Siniard, D. J., Zentner, G. E. & Wade, M. J. Preprint at bioRxiv http://dx.doi.org/10.1101/071670 (2016).
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Callaway, E. Gene drives thwarted by emergence of resistant organisms. Nature 542, 15 (2017). https://doi.org/10.1038/542015a
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DOI: https://doi.org/10.1038/542015a
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