Abstract
Design Six-month double-blind randomised trial of 186 adults who each had to least one PRCL.
Intervention Verbal and written instructions were given to participants to brush at least once a day with the allocated dentifrice. Toothbrushes and dentifrices were supplied.
Outcome measure New lesions were assessed by a single examiner using fixed clinical criteria and an electric caries monitor (ECM).
Results After 6 months, significantly more lesions in the 5000 ppm group had reversed (see Table 1). Non-cavitated lesions were more likely to harden. ECM scores in the 5000 ppm group tended to increase during the study.
Conclusions The dentifrice containing 5000 ppm fluoride was found to be significantly better at remineralising PRCL than the one containing 1100 ppm fluoride.
Acknowledgement This study was supported by a grant from Colgate Palmolive.
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References
Kelly M, Steele J, Nuttal N, et al. Adult Dental Health Survey: Oral Health in the United Kingdom 1998, London: Government Statistical Service. 2000.
Leake JL . Clinical decision making for caries management in root surfaces. J Dent Edu 2001; 65:1147–1153.
Lynch E, Baysan A, Ellwood R, Davies R, Petersson L, Borsboom P . Effectiveness of two fluoride dentifrices to arrest root carious lesions. Am J Dent 2000; 13:218–220.
American Dental Association. Council on Dental Therapeutics, Report of the workshop aimed at defining guidelines for caries clinical trials: superiority and equivalency claims for anticaries dentifrices. JADA 1988; 117:663–665.
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Address for correspondence: Aylin Baysan, St Bartholomew's and the London School of Medicine and Dentistry, Department of Adult Dental Health, Turner Street, Whitechapel, London E1 2AD, UK. E-mail: a.baysan@mds.qmw.ac.uk
Baysan A, Lynch E, Ellwood R, Davies R, Petersson L, Borsboom P. Reversal of primary root caries using dentifrices containing 5,000 and 1,100 ppm fluoride. Caries Res 2001; 35:41–46
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Leake, J. 5000 ppm toothpaste more effective than 1100 ppm in reversing root caries. Evid Based Dent 4, 9 (2003). https://doi.org/10.1038/sj.ebd.6400152
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DOI: https://doi.org/10.1038/sj.ebd.6400152
