Abstract
Data sources Index Medicus, MEDLINE were searched, as well as the bibliographies of identified studies.
Study selection Papers selected were those in which odontogenic keratocysts (OKC) was diagnosed histologically, the patient selection process was adequately described, there was consecutive, adequate description of the follow-up period, and where detailed treatment information and recurrence rates were included and assessed using eight defined criteria.
Data extraction and synthesis The treatment method and recurrence rates were extracted and tabulated.
Results Fourteen papers met the criteria. These were restricted to retrospective consecutive case-series. The type of treatment and recurrence rates are shown in the Table 1.
Conclusions The literature is limited to retrospective study designs and prospective studies need to be initiated. It appears, however, that resection or enucleation with adjunctive therapy is associated with lower recurrence rates than enucleation alone.
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References
Neville BW, Damm DD, Allen CM, Bouquot JE . Oral and Maxillofacial Pathology. 2nd Edn. Philadelphia: WB Saunders Company; 2002.
Pindborg JJ, Kramer IRH . International Histological Classification of Tumours. No. 5. Histological Typing of Odontogenic Tumours, Jaw Cysts and Allied Lesions. Geneva: World Health Organisation; 1971.
Kramer IRH, Pindborg JJ, Shear M . International Histological Classification of Tumours. No. 5. Histological Typing of Odontogenic Tumours, Jaw Cysts and Allied Lesions. 2nd Edn. Geneva: World Health Organisation; 1992.
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Address for correspondence: Ian Furst, 697 Coronation Blvd, Cambridge, Ontario, Canada N1R 3GS. E-mail: ian_furst@yahoo.com
Blanas N, Freund B, Schwartz M, Furst I M. Systematic review of the treatment and prognosis of the odontogenic keratocyst. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000; 90:553–558
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Yeo, J. Treatment of odontogenic keratocysts by enucleation with adjunctive therapy has lower recurrence rates. Evid Based Dent 4, 53–54 (2003). https://doi.org/10.1038/sj.ebd.6400203
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DOI: https://doi.org/10.1038/sj.ebd.6400203
