Abstract
Data sources
The Cochrane library, Medline, Embase, CINAHL and Scopus databases were searched.
Study selection
Cross-sectional or longitudinal studies evaluating caries prevalence in CLP patients against a suitable matched control were included.
Data extraction and synthesis
Study selection, data extraction and quality assessment were carried out independently by two reviewers. Meta-analysis was carried out using a random effects model.
Results
Seven studies (total 474 patients) met the inclusion criteria. All of the studies were cross-sectional in nature, and used the decayed, missing and filled (DMF/dmf) indices as the final outcomes. Five studies involving permanent teeth suggested that CLP patients have a higher number of DMF teeth than the controls (mean difference 1.38; p = 0.003). Four studies of primary teeth suggest that CLP patients have a higher number of dmf teeth than the controls (mean difference 1.51; p = 0.03).
Conclusions
Individuals with CLP, when compared with matched non-CLP controls, tend to have a higher prevalence of dental caries, as detected using the decayed, missing and filled index. This holds true both for permanent and for deciduous teeth. One must keep in mind, however, that relatively few studies were included in the present meta-analysis, and the reporting on the methods in the individual studies was not always transparent.
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References
Wells M . Oral health status of children with craniofacial anomalies. Pediatr Dent 2013; 35: E79–86.
Council on Clinical Affairs American Academy of Pediatric Dentistry: Guideline on caries-risk assessment and management for infants, children, and adolescents. Pediatr Dent 2013; 35: E157–164.
Lucas VS, Gupta R, Ololade O, et al. Dental health indices and caries associated microflora in children with unilateral cleft lip and palate. Cleft Palate Craniofac J 2000; 37: 447–452.
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Antonarakis GS, Palaska PK, Herzog G. Caries prevalence in non-syndromic patients with cleft lip and/or palate: a meta-analysis. Caries Res 2013; 47: 406–413. doi: 10.1159/000349911. Epub 2013 May 3. PubMed PMID: 23652859.
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Wells, M. Review suggests that cleft lip and palate patients have more caries. Evid Based Dent 15, 79 (2014). https://doi.org/10.1038/sj.ebd.6401042
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DOI: https://doi.org/10.1038/sj.ebd.6401042
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