Figure 5
From: Ciprofloxacin induces apoptosis and inhibits proliferation of human colorectal carcinoma cells
Ciprofloxacin induces mitochondrial injury of CC-531 (A) and HepG2 (B) cells. Green fluorescence of JC-1 dye was assessed as a parameter for mitochondrial breakdown. Increased green fluorescence is detectable in CC-531 cells incubated with 500 μg ml−1 ciprofloxacin for 48 h (dotted line) compared to cells treated with 10% FCS alone (black line) but not in HepG2 controls.
