Figure 1

Genomic structure of the PSE gene. Intron/exon boundaries of the PSE gene were obtained as described in Materials and Methods. The nucleotide lengths of exons 1–6 are: 1 (386), 2 (465), 3 (198), 4 (48), 5 (146), 6 (650). Lengths (in nucleotides) of introns following respective exons are: 1 (11 444), 2 (2338), 3 (1421), 4 (118), and 5 (797). Functional domains of the exons (Oettgen et al, 2000) are indicated in the top portion of the boxes. Translation start site is indicated by arrow at far left of exon 2. Arrow at the top right of exon 2 indicates approximate position of forward primer used for real-time RT–PCR analyses is indicated, while arrow below exon 3 indicates position of the reverse primer.