Figure 4 | British Journal of Cancer

Figure 4

From: Rationale for combination therapy of chronic myelogenous leukaemia with imatinib and irradiation or alkylating agents: implications for pretransplant conditioning

Figure 4

Apoptosis in EM-3 cells 24 h after start of incubation as detected by the annexin V/propidium iodide assay. Compared to treatment with imatinib alone or γ-irradiation alone (A, imatinib; B, γ-irradiation) a striking increase in the early apoptotic (lower right quadrant: annexin V+/PI−) and dead cell (upper right quadrant: annexin V+/PI+) fractions was observed (C) when the cells were treated with the combination. D, untreated cells.

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