Figure 5

Activity of imatinib combinations in primary CML progenitor cells obtained from two patients. Imatinib + γ-irradiation produced a stronger growth inhibition than either treatment alone over the whole dose range tested as opposed to imatinib + busulfan and imatinib + treosulfan. Triangles, patient 1; circles, patient 2; open symbols, monotherapy; filled symbols, combination with imatinib.