Figure 6 | British Journal of Cancer

Figure 6

From: Rationale for combination therapy of chronic myelogenous leukaemia with imatinib and irradiation or alkylating agents: implications for pretransplant conditioning

Figure 6

Effects of γ-irradiation, busulfan or treosulfan (each±1.0 μM imatinib) on BCR–ABL-negative cells: ED50 values of γ-irradiation, busulfan or treosulfan alone and the respective ED50 values in combination with imatinib do not differ significantly. Addition of imatinib does not increase the cytotoxicity on BCR–ABL-negative cells. White columns, cytotoxic treatment alone; hatched columns, respective combination with imatinib; bars, 1 s.d. Means of three paired experiments are presented (P>0.05).

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