Figure 3
From: Investigations on a clinically and functionally unusual and novel germline p53 mutation
FASAY results. The FASAY gave a normal wild-type result with only 3% red colonies when mRNA was extracted from the patients PHA-stimulated leukocytes. In contrast the 7 base pair mutation synthesised by site directed mutagenesis gave 100% red colonies. The 344P mutation, which is an inactive mutant, also gave 100% red colonies and wild-type p53 gave only 2% red colonies.
