Figure 2 | British Journal of Cancer

Figure 2

From: Transforming Growth Factor-β2 protects the small intestine during methotrexate treatment in rats possibly by reducing stem cell cycling

Figure 2

(A,B) Epithelial cells are protected against cell cycle specific drug, due to TGF-β2 present in TGF-β2 enriched fraction. Cell viability of IEC-6 cells after treatment with a concentration range of Ara-C (A) or MTX (B), incubated with (closed triangle) or without (closed square) TGF-β2 enriched fraction is shown. The open triangles (A) show cells, which were incubated with TGF-β2 enriched fraction after blocking of TGF-β2 activity by pre-incubation with anti-TGF-β2 antibodies. Mean±s.d. of three individual experiments is shown. Statistical differences between viability of cells incubated with TGF-β2 enriched fraction after depletion for TGF-β2 and control or TGF-β2 alone are indicated with #(P<0.05) or *(P<0.01).

Back to article page