Figure 3

Angiogenesis in 4TI mammary fat pad tumours. Representative sections of tumours stained for CD31 from control mice (A), SC-236 treated (B), and indomethacin treated mice (C) are shown. Original magnification×200. (D) Microvessel density was assessed by light microscopy following CD31 staining (one section from each of six mice per group). For each section, vessels were counted in five high power fields (200×magnification (×20 objective and ×10 ocular)). Data is expressed as mean number of vessels per h.p.f.±s.e.m. *P<0.05 vs control.