Figure 2

Representative results of Mlh1 and Msh2 immunostaining in human normal and carcinomatous colorectal tissues. A and B, Poorly-differentiated carcinoma cells (B) show no nuclear staining for Mlh1 while normal crypt epithelium (A) shows nuclear staining; (C) Normal crypt epithlium shows nuclear staining for Msh2; (D), Moderately-differentiated carcinoma cells show nuclear staining for Msh2