Figure 5
From: A phase I and pharmacokinetic study of MAG-CPT, a water-soluble polymer conjugate of camptothecin
The percentage decreases in WBC (solid line) and ANC (dashed line) during the first course vs the daily dose. The lines indicate the best fit of the data to the sigmoidal maximal effect pharmacodynamic model (coefficient of correlation is 0.75 and 0.84 for WBC and ANC, respectively).
