Figure 2 | British Journal of Cancer

Figure 2

From: Genomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel mutation detection approach

Figure 2

(A) Family C149. The index patient had a double colonic tumour at age 32, his father had colonic cancer preceded by skin tumours including Muir–Torre syndrome skin lesions (sebaceous gland adenoma, kerato-acanthoma, planocellular cancer). Patient 1-2 had primary cancers of the vulva and stomach. (B) Family C293. The index patient had colonic cancer at the age of 21 years. His unaffected mother had a tubular adenoma on colonoscopic screening, his maternal grandmother had late-onset colonic cancer. Family members I-2 (C149) and I-1 (C293) have a common ancestor.

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