Figure 1

High-density cDNA microarray analysis. Validation in expression of selected genes from 21 68 clones in six gastric cancer cell lines. Data are represented in a matrix format: each row represents a single gene, and each column an experimental sample. In each sample, the ratio of the number of transcripts of each gene to the medium abundance of the gene's transcript among all the cell lines is represented by the colour of the corresponding cell in the matrix. Green square,transcript level below the median; black squares, transcript levels equal to the medium; red squares, transcript levels greater than the median. Colour saturation reflects the magnitude of the ratio relative to the median for each set of samples. (A) Cluster analysis of selected genes of six gastric cancer cell lines using the RIKEN cDNA microarray. Bars to the right identify the location of the inserts displayed in panels B and C. (B) Up-regulated genes in gastric cancer cells from malignant ascites. (C) Down-regulated genes in gastric cancer cells from malignant ascites