Table 1 Detection of VEGF-C, VEGF-D and VEGFR-3 in ovarian tumours

From: Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinoma

  

VEGF-C detection (%)

VEGF-D detection (%)

VEGFR-3 detection (EC) (%)

Tissues

No. of patients

0

<10%

10–50%

50% <

0

<10%

10–50%

50% <

Negative

Positive

Benign tumour

20

12(60.0)

8(40.0)

0

0

14(70.0)

6(30.0)

0

0

18(90.0)

2(10.0)

Borderline tumour

11

4(36.4)

5(45.4)

2(18.2)

0

6(54.5)

3(27.3)

2(18.2)

0

8(72.7)

3(27.3)

Carcinoma

59

0

20(33.9)

17(28.8)

22(37.3)

4(6.8)

18(30.5)

22(37.3)

15(25.4)

25(42.4)

34(57.6)

  1. The incidence of VEGF-C and VEGF-D detected in carcinomas was significantly higher than that detected in benign tumours (Mann–Whitney U-test, P<0.0001, respectively) and borderline tumours (Mann–Whitney U-test, P=0.0002 and 0.0007, respectively). The frequency of VEGFR-3 detected in carcinomas was significantly higher than that detected in benign tumours (χ2 P<0.0002) and high with a marginal significance compared to that detected in borderline tumours (χ2, P=0.06). There was no significant difference in the levels of VEGF-C, VEGF-D and VEGFR-3 positivity between samples of benign and borderline tumours.
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