Table 1 Repetitive treatment of multicellular glioblastoma spheroids with temozolomide
From: Temozolomide induces apoptosis and senescence in glioma cells cultured as multicellular spheroids
Second treatment | |||
|---|---|---|---|
First treatment | IC 50 after 8 days | IC 50 after 13 days | IC 30 after 13 days |
Untreated | 9.8±1.3 μg ml−1 | 14.0±1.6 μg ml−1 | 5.7±1.9 μg ml−1 |
10 μg ml−1 temozolomide | Not reached | Not reached | 13 μg ml−1 |
20 μg ml−1 temozolomide | Not reached | Not reached | 13 μg ml−1 |
