Figure 3
Radiochromatograms of 32P-postlabelled DNA adducts in DNA of MCF-7 cells following incubation with (A) medium alone, (B) 10 nM, (C) 100 nM, (D) 1 μ M and (E) 10 μ M 5F 203 for 72 h. Adducts were enriched by butanol extraction prior to postlabelling and separated by HPLC. Note the y scale of chromatograms for control, 10 and 100 nM is 1000 c.p.m. while the scale for 1 and 10 μ M is 20 000 c.p.m. to aid resolution of the adduct profile.
