Table 1 Synovial sarcoma gene cluster

From: Molecular classification of synovial sarcomas, leiomyosarcomas and malignant fibrous histiocytomas by gene expression profiling

Clone ID

UG cluster a

Symbol

Gene product

245330

Hs.349109

IGF2

Insulin-like growth factor 2

245330

Hs.349109

IGF2

Insulin-like growth factor 2

754406

Hs.172631

ITGAM b

Integrin, α M

754406

Hs.172631

ITGAM b

Integrin, α M

2242404

Hs.105445

GFRA1 b

GDNF family receptor α 1

383188

Hs.80539

RCV1

Recoverin

48799

Hs.78854

ATP1B2 b

ATPase, Na+/K+ transporting, β 2 polypeptide

197520

Hs.225977

NCOA3 b

Nuclear receptor coactivator 3

742082

Hs.1872

PCK1 b

Phosphoenolpyruvate carboxykinase 1

950680

Hs.108327

DDB1

Damage-specific DNA binding protein 1

594633

Hs.5338

CA12 b

Carbonic anhydrase XII

145112

Hs.168383

ICAM1 b

Intercellular adhesion molecule 1 (CD54)

725473

Hs.16349

KIAA0431 b

KIAA0431

85259

 

b

Genomic matching AL137072 at 9q31.1

232933

Hs.10755

DPYS b

Dihydropyrimidinase

297061

Hs.10755

DPYS b

Dihydropyrimidinase

753923

Hs.1334

MYB b

MYB transcription factor

80910

Hs.183556

SLC1A5 b

Solute carrier family member 5

427750

Hs.1985

SPTA1 b

Spectrin, α, erythrocytic 1

384078

Hs.106876

ATP6V0D1 b

ATPase, H+ transporting V0 subunit d isoform 1

758343

Hs.173125

PPIF b

Peptidylprolyl isomerase F

46196

Hs.19261

DYT1 b

Dystonia 1

884283

Hs.283742

b

Retrotransposon

42331

Hs.91916

clone 23892 b

Hypothetical protein

267865

 

b

Genomic matching AC104070 at 4q35.2

795325

  

Genomic matching AL049796 at 1p22-31.1

211548

Hs.73858

CPN2

Carboxypeptidase N, polypeptide 2

1589786

Hs.111

FGF9 b

Fibroblast growth factor 9

210575

Hs.2288

VSNL1 b

Visinin-like 1

277507

Hs.75652

GSTM5 b

Glutathione S-transferase M5

52430

Hs.23106

TRAP100 b

Thyroid hormone receptor-associated protein (100 kDa)

756968

Hs.144700

EFNB1 b

Ephrin-B1

502333

Hs.49765

VLCS-H1 b

Very long chain acyl-CoA synthetase homolog1

135085

Hs.154782

AP3S2

Adaptor-related protein complex 3, σ 2 subunit

270626

Hs.106415

PPARD b

Peroxisome proliferative activated receptor, δ

251019

Hs.194657

CDH1 b

Cadherin 1 , E-cadherin

291290

Hs.278632

SSX4 b

Synovial sarcoma, X breakpoint 4

727251

Hs.1244

CD9

CD9 antigen

49959

Hs.179747

EVI5

Ectopic viral integration site 5

809598

Hs.151051

MAPK10

Mitogen-activated protein kinase 10

23173

Hs.151051

MAPK10

Mitogen-activated protein kinase 10

221846

Hs.211773

CHES1 b

Checkpoint suppressor 1

177737

Hs.29117

PURA b

Purine-rich element-binding protein A

773554

Hs.289043

SPIN b

Spindlin

813742

Hs.82848

SELL

Selectin L

797048

Hs.68879

BMP4 b

Bone morphogenetic protein 4

813520

Hs.372513

GYPB b

Glycophorin B

233078

Hs.11711

KIAA0329 b

KIAA0329

  1. aDNA sequencing was used to confirm the identity of all genes in this table.
  2. bGenes with levels of expression statistically significant different (corrected P=0.01) in synovial sarcomas compared to sarcomas in other groups by Wilcoxon – Mann – Whitney test utilising Benjamini and Hochberg false discovery rate to correct for multiple testing.