Table 1 Results of experiments of irradiation with 10 3He2+ particles of 10 individual cell nuclei each distributed on the periphery of a 7-day-old human ureter explant outgrowth

From: A proliferation-dependent bystander effect in primary porcine and human urothelial explants in response to targeted irradiation

 

Control

Irradiated

 

Sample

Mean number of damaged cells

Mean calculated number of cells within explant outgrowth ( mC)

Mean fraction of damaged cells ± s.d. ( fC)

Mean number of damaged cells

Mean calculated number of cells within explant outgrowth ( mI)

Mean fraction of damaged cells ± s.d. ( fI)

Mean calculated number of additionally damaged cells a

1

2433

7.8 × 105

0.0031±0.0004

7074

6.4 × 105

0.0111±0.0051

5689

2

3279

7.0 × 105

0.0047b

6267

6.1 × 105

0.0102±0.0032

3608

3

3075

5.0 × 105

0.0062±0.0004

5217

4.9 × 105

0.0106±0.0022

2174

4

2604

6.1 × 105

0.0043±0.0012

4215

5.9 × 105

0.0071±0.0015

1679

aMean number of additionally damaged cells is equal to (fIfC) × (mC+mI)/2.

bSingle explant only.