Table 2 Results of experiments of irradiation with 10 3He2+ particles of 10 individual cell nuclei each distributed on the periphery of a 7-day-old porcine ureter explant outgrowth

From: A proliferation-dependent bystander effect in primary porcine and human urothelial explants in response to targeted irradiation

 

Control

Irradiated

 

Sample

Mean number of damaged cells

Mean calculated number of cells within explant outgrowth ( mC)

Mean fraction of damaged cells ± s.d. ( fC)

Mean number of damaged cells

Mean calculated number of cells within explant outgrowth ( mI)

Mean fraction of damaged cells ± s.d ( fI)

Mean calculated number of the additionally damaged cells a

1

2663

6.2 × 105

0.0043±0.0013

4215

5.9 × 105

0.0071±0.001

1698

2

2093

4.5 × 105

0.0046b

2617

4.3 × 105

0.0061±0.0012

663

3

2039

8.5 × 105

0.0024±0.0008

4874

8.0 × 105

0.0061±0.0011

3050

4

918

6.6 × 105

0.0014±0.0011

3568

6.6 × 105

0.0054±0.0009

2633

5

1257

7.9 × 105

0.0016±0.0009

5236

7.9 × 105

0.0066±0.0014

3948

aMean number of additionally damaged cells is equal to (fIfC) × (mC+mI)/2.

bSingle explant.