Table 3 Relation between maspin mRNA level and the standard clinical, pathological and biological factors
From: Prognostic value of maspin mRNA expression in ERα-positive postmenopausal breast carcinomas
maspin mRNA level | |||||
|---|---|---|---|---|---|
Number of patients (%) | |||||
Total population (%) | Underexpression | Normal | Overexpression | P -value a | |
Total | 105 (100.0) | 33 (31.4) | 48 (45.7) | 24 (22.9) | |
Age (years) | NS | ||||
⩽70 | 52 (49.5) | 15 (45.5) | 27 (56.2) | 10 (41.7) | |
70 | 53 (50.5) | 18 (54.5) | 21 (43.8) | 14 (58.3) | |
Histological gradeb,c | 0.03 | ||||
I+II | 80 (76.9) | 27 (81.8) | 40 (83.3) | 13 (56.5) | |
III | 24 (23.1) | 6 (18.2) | 8 (16.7) | 10 (43.5) | |
Lymph node status | NS | ||||
0 | 17 (16.2) | 5 (15.2) | 7 (14.6) | 5 (20.8) | |
1–3 | 59 (56.2) | 15 (45.4) | 32 (66.7) | 12 (50.0) | |
>3 | 29 (27.6) | 13 (39.4) | 9 (18.7) | 7 (29.2) | |
Macroscopic tumour size (mm) | NS | ||||
⩽30 | 73 (69.5) | 22 (66.7) | 34 (70.8) | 17 (70.8) | |
>30 | 32 (30.5) | 11 (33.3) | 14 (29.2) | 7 (29.2) | |
Histological type | NS | ||||
Ductal | 97 (92.4) | 32 (97.0) | 42 (87.5) | 23 (95.8) | |
Lobular | 8 (7.6) | 1 (3.0) | 6 (12.5) | 1 (4.2) | |
ERBB2 RNA status | NS | ||||
Overexpressed | 18 (17.1) | 3 (9.1) | 8 (16.7) | 7 (29.2) | |
Normal | 87 (82.9) | 30 (90.9) | 40 (83.3) | 17 (70.8) | |
ERβ RNA statusc | NS | ||||
Low | 36 (34.6) | 14 (42.4) | 15 (31.9) | 7 (29.2) | |
Intermediate | 34 (32.7) | 7 (21.2) | 17 (36.2) | 10 (41.6) | |
High | 34 (32.7) | 12 (36.4) | 15 (31.9) | 7 (29.2) | |
