Table 1 Immunofluorescence staining patterns of adhesion molecules on EMT6 microvessels following PDT

From: Role of cytokines in photodynamic therapy-induced local and systemic inflammation

 

Time after PDT (h)

Adhesion molecule

None

HPPH

0

1

3

6 (PDT)

6 (Untx) a

8

12

24

48

E-selectin (CD62E)

−b

−

−/±

−/±

−/+

−/+++

−

−/+

−/±

−/±

−

ICAM-1 (CD54)

−/±

−/±

−/+

−/+

−/++

−/±

−/++

−/++

−/+

−/+

−/±

PECAM-1 CD31

+++

+++

+++

+++

+++

++++

+++

++

−/++

NDc

ND

  1. aUntx refers to the contralateral tumour that was not treated with light in animals receiving HPPH and having one tumour treated with light.
  2. bStaining intensity of tumour microvessels ranges from undetectable (−) to very high levels (++++).
  3. cND, not determined.
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