Table 3 Comparison of the performance of PGA/PGC ratio as a diagnostic test to detect histological lesions acccording to gender and age. Results of the Eurohepygast study
Diagnosis of ACG a | Diagnosis of corpus or multifocal atrophy | ||||
|---|---|---|---|---|---|
Global sample | Men | Women<41 years old | Women ⩾ 41 years old | Global sample | |
n =289 | n =117 | n =70 | n =102 | n =289 | |
Area under ROC curve | 0.73 | 0.75 | 0.76 | 0.68 | 0.84 |
Cut-off point | 5.6 | 5.6 | 6.4 | 5.6 | 4.7 |
Sensitivity (%) | 65.1 | 64 | 75 | 69.2 | 77.1 |
95% CIb | 52.7, 76.1 | 44.1, 80.8 | 45.9, 93.2 | 49.8, 84.6 | 61.2, 88.8 |
Specificity (%) | 77.9 | 84.8 | 70.7 | 65.8 | 87.4 |
95% CIb | 72.1, 82.9 | 76.3, 91.1 | 58.1, 81.3 | 54.6, 75.8 | 82.9, 91.1 |
PPVc (%) | 45.1 | 53.3 | 34.6 | 40.9 | 45.8 |
95% CIb | 35.1, 55.3 | 35.6, 70.5 | 18.4, 54.1 | 27.2, 55.8 | 33.4, 58.5 |
NPVd (%) | 88.9 | 89.6 | 93.2 | 86.2 | 96.5 |
95% CIb | 83.9, 92.7 | 81.9, 94.8 | 82.6, 98.2 | 75.5, 93.4 | 93.5, 98.4 |
Accuracy (%) | 75.1 | 80 | 71.4 | 66.7 | 86.2 |
