Figure 3
Growth of B16 parental and cytokine-transfected tumour cells in vitro and in vivo in GFP mice. (A) 1 × 105 parental (circles) or IL-12-transfected (squares) B16 tumour cells were plated in vitro. At daily intervals, cells were removed from triplicate plates and counted individually. Points are the mean and standard deviation of the counts. (B) 2 × 105 parental (circles), or 1 × 106 B16/IL-12 (squares) tumour cells were implanted intramuscularly in the leg of syngeneic C57BL/6-H-2KbP-GFP mice and tumour growth followed by measuring the leg diameter. Each line represents tumour growth in an individual mouse.
