Figure 8

Effects of Ad5WS1 and Ad/K1–5, singly or in combination, on human TCC-SUP bladder tumour xenograft growth. TCC-SUP cells (107) were inoculated s.c. into the flank of SCID mice at day 0. At day 8 when visible and palpable nodules developed at all injection sites, groups of seven mice were treated intratumorally with Ad5WS1 (108 PFU) or Ad/K1–5 (2.5 × 108 PFU) alone for 5 consecutive days, or with Ad5WS1 (108 PFU) for 5 consecutive days plus Ad/K1–5 (2.5 × 108 PFU) at days 9 and 11. Data are presented as mean±s.e.