Table 3 Pathological response rate to neoadjuvant treatment
No. of patients (%) | |||
|---|---|---|---|
Pathological response | Overall ( n =76) | Group 1 ( n =42) | Group 2 ( n =34) |
Restricted Chevallier's classification | |||
Class 1: no tumour in breast (pCR) | 10 (13.2) | 3 (7.1) | 7 (20.6) |
Class 2: in situ carcinoma only | 5 (6.6) | 2 (4.8) | 3 (8.8) |
Class 3: invasive carcinoma with alteration | 41 (53.9) | 26 (61.9) | 15 (44.1) |
Class 4: unmodified invasive carcinoma | 20 (26.3) | 11 (26.2) | 9 (26.5) |
ORR (Classes 1+2) No. (%; 95% CI) | 15 (19.8; 10.8–28.8) | 5 (11.9; 4.1–25.9) | 10 (29.4; 14.1–44.7) |
Sataloff's classification | |||
Class A: complete+quasicomplete response | 27 (35.5) | 13 (30.9) | 14 (41.2) |
Class B: partial response | 11 (14.5) | 6 (14.3) | 5 (14.7) |
Class C: minor response | 18 (23.7) | 12 (28.6) | 6 (17.7) |
Class D: no response | 20 (26.3) | 11 (26.2) | 9 (26.4) |
ORR (Class A) No. (%; 95% CI) | 27 (35.5; 24.7–46.3) | 13 (30.9; 16.9–44.9) | 14 (41.2; 24.7–57.7) |
