Figure 1

Staining of STAT1, STAT3 and STAT5 on serial pathological sections of a NPC biopsy specimen. (A) H&E stain. Large, vesicular nucleus with prominent nucleolus (arrow) is noted in majority of the tumour cells. (B) Strong intranuclear (arrowheads) and cytoplasmic staining of STAT3. (C) intranuclear (arrows) and faint cytoplasmic staining of STAT5. Nuclear STAT5 staining is also noted in endothelial cells of a nearby vessel (arrowheads). (D) No nuclear staining of STAT1 in the tumour cells (arrows). Nuclear staining of STAT1 is noted in an infiltrating lymphocyte (arrowhead) (original magnification Ă— 1000).