Figure 1

Hazard ratio (HR) and 95% CI of mortality in studies evaluating Bcl-2 status by IHC with Ab 100. χ2 statistic for heterogeneity=8.14, 4 df, P=0.09. NB: HR<1 implies a survival benefit for the group with positive Bcl-2. The square size is proportional to the number of patients included in the study. The centre of the lozenge gives the combined HR of the meta-analysis and its extremities the 95% CI.