Table 1 Effect of uPAR suppression on the proliferative and adhesive response of HCT116 cell lines

From: Downregulation of urokinase plasminogen activator receptor expression inhibits Erk signalling with concomitant suppression of invasiveness due to loss of uPAR–β1 integrin complex in colon cancer cells

Cell type

MTT response (absorbance at 595 nm)

Adhesive response (absorbance at 595 nm)

HCT116 (mock)

1.54±0.16

0.74±0.04

HCT116 (A/S)

1.34±0.22

0.58±0.01*

Results are shown as mean±S.E.M of three different experiments performed in triplicate. *Significantly different, P<0.002, compared to mock-transfected cells.

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