Figure 2
From: High frequency of mitochondrial genome instability in human endometrial carcinomas
Detection of mtMSI in endometrial carcinomas by DNA sequencing. (A) The normal sequence (commencing at np 514, arrows) of U111 (Table 1) is a microsatellite DNA containing four CA repeats. In the tumour, it was expanded to carry five CA repeats. (B) The mtDNA sequence found in the normal tissue of U109 (Table 1) contained heteroplasmic stretch of C residues, comprising C8, C9, C10 and C11 (commencing at np 303, arrows). In the tumour, mtDNA sequence contained mainly C8 and a small proportion of C9.
