Table 1 Somatic mtDNA mutations found in human endometrial carcinomas

From: High frequency of mitochondrial genome instability in human endometrial carcinomas

Code no.	Gene	Location	Mutation type	Wild type ^a	Normal	Tumour
U9	D-loop	289–346	Deletion	Normal length	Normal length	50-bp deletion
G12	D-loop	152	Point mutation	T	T	C
U34	D-loop	251	Point mutation	G	G	G, A
U10	D-loop	294	Point mutation	T	T	T, C
U27	12S RNA	650	Point mutation	T	T	T, C
U59	12S RNA	817	Point mutation	G	G	A
G29	12S RNA	879	Point mutation	T	T	C
U44	16S RNA	3163	Point mutation	G	G	A
U111	D-loop	514–523	mtMSI	(CA)₅	(CA)₄	(CA)₅
U24	12S RNA	956–960	mtMSI	C5	C5	C4, C5
U32	12S RNA	956–960	mtMSI	C5	C6	C6, C7
U120	12S RNA	956–960	mtMSI	C5	C6	C7
U27	12S RNA	956–965	mtMSI	CCCCCTCCCC	C11, C12, C13, C14	C12, C13, C14
U10	D-loop	303–309	mtMSI	C7	C8, C9	C8
U12	D-loop	303–309	mtMSI	C7	C7, C8, C9	C8
U24	D-loop	303–309	mtMSI	C7	C8, C9	C9, C10
U42	D-loop	303–309	mtMSI	C7	C7, C8, C9	C8, C9, C10
U44	D-loop	303–309	mtMSI	C7	C7, C8, C9	C8, C9, C10, C11
U46	D-loop	303–309	mtMSI	C7	C7, C8, C9	C8, C9, C10, C11
U52	D-loop	303–309	mtMSI	C7	C7, C8, C9	C8, C9, C10
U55	D-loop	303–309	mtMSI	C7	C8, C9, C10	C9, C10
U56	D-loop	303–309	mtMSI	C7	C8, C9	C8
U109	D-loop	303–309	mtMSI	C7	C8, C9, C10, C11	C8, C9
U120	D-loop	303–309	mtMSI	C7	C8, C9, C10	C8
U125	D-loop	303–309	mtMSI	C7	C8, C9, C10	C8, C9
G24	D-loop	303–309	mtMSI	C7	C7, C8, C9	C7, C8
G27	D-loop	303–309	mtMSI	C7	C7	C7, C8
G35	D-loop	303–309	mtMSI	C7	C9, C10	C9, C10, C11
G81	D-loop	303–309	mtMSI	C7	C8, C9, C10	C9, C10, C11
U9	D-loop	16184–16193	mtMSI	CCCCCTCCCC	C13	C14
U25	D-loop	16184–16193	mtMSI	CCCCCTCCCC	C11	C12
U37	D-loop	16184–16193	mtMSI	CCCCCTCCCC	C12	C10, C11, C12
U44	D-loop	16184–16193	mtMSI	CCCCCTCCCC	C10	C10, C11, C12
U51	D-loop	16184–16193	mtMSI	CCCCCTCCCC	C11, C12, C13	C12, C13, C14
U58	D-loop	16184–16193	mtMSI	CCCCCTCCCC	C12	C11
G29	D-loop	16184–16193	mtMSI	CCCCCTCCCC	C7	C7, C8, C9, C10

Table entries in bold font indicate the predominant sequence variants in heteroplasmic mixtures.
^aWild type indicates the nucleotide(s) in the Revised Cambridge reference sequence (GenBank NC_001807).

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Table 1 Somatic mtDNA mutations found in human endometrial carcinomas

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