Table 3 Time ratios from the generalised gamma AFT model for the lung cancer trial
From: Survival Analysis Part II: Multivariate data analysis – an introduction to concepts and methods
Univariate analysis | Multivariate analysis | |||||||
|---|---|---|---|---|---|---|---|---|
Covariate | Coefficient ( bi) | TR exp( bi) | 95% CI | P -value | Coefficient ( bi) | TR exp( bi) | 95% CI | P -value |
Treatment (RT+CAP vs RT alone) | 0.648 | 1.91 | (1.21–3.01) | 0.005 | 0.718 | 2.05 | (1.29–3.23) | 0.002 |
Cell type (Sq vs non-Sq) | 0.506 | 1.66 | (1.01–2.71) | 0.04 | 0.511 | 1.67 | (1.04–2.68) | 0.03 |
Performance status (8–10 vs 5–7) | 0.767 | 2.15 | (1.11–4.19) | 0.02 | 0.729 | 2.07 | (1.00–4.29) | 0.05 |
Tumour status | 0.59 | 0.60 | ||||||
1 | (0.000) | (1.00) | — | (0.000) | (1.00) | — | ||
2 | −0.189 | 0.83 | (0.40–1.70) | −0.353 | 0.70 | (0.35–1.41) | ||
3 | −0.388 | 0.68 | (0.31–1.48) | −0.378 | 0.69 | (0.31–1.53) | ||
Nodal involvement | 0.87 | 0.97 | ||||||
None | (0.000) | (1.00) | — | (0.000) | (1.00) | — | ||
Limited | 0.122 | 1.13 | (0.46–2.79) | −0.059 | 0.94 | (0.36–2.48) | ||
Extensive | 0.206 | 1.23 | (0.55–2.73) | 0.029 | 1.03 | (0.42–2.54) | ||
Age at diagnosis (/years) | −0.013 | 0.99 | (0.96–1.01) | 0.34 | −0.011 | 0.99 | (0.96–1.01) | 0.41 |
Gender (male vs female) | 0.032 | 1.03 | (0.62–1.71) | 0.90 | −0.007 | 0.99 | (0.59–1.67) | 0.98 |
Weight loss (⩾10 vs <10%) | −0.477 | 0.62 | (0.29–1.33) | 0.22 | −0.337 | 0.71 | (0.34–1.51) | 0.38 |
Race (white vs non-white) | 0.440 | 1.55 | (0.81–2.98) | 0.19 | 0.202 | 1.22 | (0.61–2.46) | 0.57 |
