Table 3 Odds ratios, 95% confidence intervals (CI) and P-values for a higher Wolfe gradea associated with an s.d. increase in birth weight, age at menarche, age-specific heights and interval-specific height velocities

From: Life-course body size and perimenopausal mammographic parenchymal patterns in the MRC 1946 British birth cohort

 

Observed data only

Including imputed values where missing and controlling for:

   

Crude

Crude ( N =1263)

Age at mammography, BMI at age 53 years and breast size ( N =1253)

All other height components, age at mammography, breast size, BMI age 53 ( N =1253)

 

n b

Mean (s.d.)

Odds ratio a

95% CI

Odds ratio a

95% CI

Odds ratio a

95% CI

P-value

Odds ratio a

95% CI

P-value

Birth weight (g)

 

1294

3318 (468)

1.03

0.93, 1.14

—

—

1.03c

0.92, 1.15

0.59

—

—

—

Age at menarche (years)

 

1214

13.0 (1.3)

1.26

1.13, 1.40

—

—

1.14c

1.01, 1.27

0.03

—

—

—

Height (cm) at age

 2

1033

84.7 (4.6)

1.15

1.02, 1.29

1.09

0.98, 1.21

1.13

1.01, 1.26

0.03

1.07

0.94, 1.22

0.31

 4

1123

102.9 (5.0)

0.96

0.86, 1.08

0.96

0.86, 1.07

0.94

0.84, 1.05

0.25

—

—

—

 7

1122

119.8 (5.5)

0.97

0.86, 1.08

0.94

0.85, 1.05

0.93

0.84, 1.04

0.22

—

—

—

 11

1090

141.2 (7.0)

0.85

0.76, 0.95

0.88

0.79, 0.97

0.89

0.80, 1.00

0.04

—

—

—

 15

1002

158.7 (6.2)

0.95

0.84, 1.07

0.99

0.89, 1.10

0.96

0.86, 1.07

0.47

—

—

—

 36

1174

162.5 (6.3)

1.07

0.96, 1.20

1.08

0.97, 1.20

1.03

0.93, 1.15

0.55

—

—

—

Height velocity (cm/year) during ages

 2–4

966

7.94 (2.2)

0.87

0.77, 0.98

0.87

0.78, 0.97

0.82

0.74, 0.92

<0.001

0.85

0.76, 0.96

0.01

 4–7

1015

6.10 (1.4)

0.97

0.86, 1.08

0.98

0.88, 1.09

1.00

0.90, 1.12

0.97

0.97

0.86, 1.09

0.60

 7–11

1030

5.64 (1.1)

0.85

0.76, 0.96

0.88

0.80, 0.98

0.92

0.82, 1.02

0.13

1.00

0.86, 1.15

0.96

 11–15

950

4.77 (1.3)

1.19

1.05, 1.34

1.18

1.06, 1.31

1.11

1.00, 1.24

0.06

1.11

0.99, 1.24

0.08

 15–adulthood

927

1.07 (1.0)

1.22

1.08, 1.38

1.18

1.06, 1.32

1.15

1.03, 1.29

0.01

1.16

1.03, 1.29

0.01

  1. Common odds ratio associated with 1 s.d. increase in explanatory variable for three binary outcomes: (DY vs P2,P1,N1), (DY,P2 vs P1,N1) and (DY,P2,P1 vs N1).
  2. Number of women with nonmissing data for analyses on observed data only (excluding imputed values).
  3. Observed data only, that is, no imputed values.
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