Table 4 Univariate analysis of biological parameters in relation to various clinical endpoints

From: GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer: relationship with vascularity and proliferation as predictors of outcome of ARCON

 

End point

 

Local control

Time to distant metastastis

Cause-specific survival

Overall survival

Parameter

χ 2

P -value

χ 2

P -value

χ 2

P -value

χ 2

P -value

GLUT1

1.56

0.21

0.22

0.64

5.84

0.016

8.06

0.0045

CAIX

0.82

0.36

0.29

0.59

4.16

0.041

8.57

0.0034

Ki-67

2.23

0.14

1.39

0.24

0.63

0.43

0.006

0.94

MVD

0.068

0.79

0.011

0.92

0.002

0.96

0.07

0.79

Hot spot

1.40

0.23

0.013

0.91

0.57

0.45

0.001

0.98

GLUT1=glucose transporter-1 protein; CAIX=carbonic anhydrase IX. Each parameter was categorised according to the median value; MVD=mean vascular density.

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