Table 2 Distribution of cases and controls, associated odds ratios (OR) and 95% confidence intervals (CI) by vitamin K status

From: Vitamin K and childhood cancer: a report from the United Kingdom Childhood Cancer Study

  

Leukaemia

  

Vitamin K status

All cancers ( n =2530)

Total ( n =1174)

ALLa (n =1001)

Other cancersb (n =1356)

Controls ( n =4487)

Number (%)

 Intramuscular

991 (39%)

456 (39%)

394 (39%)

535 (39%)

1868 (42%)

 Oral

376 (15%)

181 (15%)

154 (15%)

195 (14%)

663 (15%)

 Given but route unknown

455 (18%)

233 (20%)

199 (20%)

222 (16%)

815 (18%)

 Not given

106 (4%)

39 (3%)

30 (3%)

67 (5%)

162 (4%)

 No record

602 (24%)

265 (23%)

224 (22%)

337 (25%)

979 (22%)

OR (95% CI) c

 Intramuscular

1.0

1.0

1.0

1.0

 Oral

1.09 (0.94–1.27)

1.13 (0.92–1.38)

1.11 (0.90–1.38)

1.06 (0.87–1.29)

 Given but route unknown

1.05 (0.91–1.22)

1.19 (0.99–1.43)

1.16 (0.95–1.41)

0.95 (0.79–1.14)

 Not given

1.24 (0.95–1.61)

1.07 (0.74–1.55)

0.98 (0.65–1.49)

1.39 (1.03–1.90)*

 No record

1.15 (1.01–1.31)*

1.18 (0.99–1.41)

1.19 (0.99–1.44)

1.12 (0.95–1.32)

  1. aALL=Acute lymphoblastic leukaemia.
  2. bCancers other than leukaemia.
  3. cCalculated using logistic regression with adjustment for age at diagnosis (single years), sex and region of residence.
  4. *P<0.05.