Table 4 Odds ratios (ORs) and 95% confidence intervals (CIs) for adenocarcinomas and squamous cell carcinomas of the cervix in relation to smoking
Adenocarcinoma | Squamous cell carcinoma | Squamous vs adenocarcinoma | |||||||
|---|---|---|---|---|---|---|---|---|---|
Cases/controls | OR a | 95% CI | Cases/controls | OR b | 95% CI | Squamous/adeno cases | OR c | 95% CI | |
Smoking status | |||||||||
Never | 72/394 | 1.00 | 121/394 | 1.00 | 121/72 | 1.00 | |||
Ever | 108/529 | 0.80 | 0.56–1.13 | 270/529 | 1.05 | 0.79–1.40 | 270/108 | 1.50 | 0.99–2.27 |
Past | 32/181 | 0.75 | 0.46–1.20 | 60/181 | 0.70 | 0.47–1.03 | 60/32 | 1.05 | 0.60–1.85 |
Current | 76/348 | 0.82 | 0.56–1.21 | 210/348 | 1.26 | 0.93–1.71 | 210/76 | 1.74 | 1.11–2.71 |
Age started smoking | |||||||||
Never | 72/394 | 1.00 | 121/394 | 1.00 | 121/72 | 1.00 | |||
10–16 years | 60/300 | 0.71 | 0.47–1.08 | 165/300 | 1.07 | 0.77–1.47 | 165/60 | 1.68 | 1.04–2.72 |
17+ years | 48/229 | 0.91 | 0.59–1.38 | 105/229 | 1.04 | 0.74–1.47 | 105/48 | 1.31 | 0.80–2.16 |
Heterogeneity between groups within ever smokers | P=0.1 | P=0.8 | P=0.06 | ||||||
Total duration for current smokers | |||||||||
Never/<1 month | 72/394 | 1.00 | 121/394 | 1.00 | 121/72 | 1.00 | |||
⩽10 years | 8/43 | 0.85 | 0.34–2.12 | 22/43 | 0.69 | 0.35–1.37 | 22/8 | 1.08 | 0.40–2.91 |
10–20 years | 37/192 | 0.72 | 0.44–1.18 | 116/192 | 1.13 | 0.79–1.62 | 116/37 | 1.66 | 0.96–2.85 |
20+ years | 31/113 | 0.80 | 0.46–1.39 | 72/113 | 2.05 | 1.29–3.26 | 72/31 | 2.44 | 1.26–4.72 |
Trend within current smokers | P=0.3 | P=0.05 | P=0.04 | ||||||
Intensity (cigarettes per day) for current smokers | |||||||||
Never | 72/394 | 1.00 | 121/394 | 1.00 | 121/72 | 1.00 | |||
<15 | 39/194 | 0.72 | 0.45–1.15 | 109/194 | 1.28 | 0.90–1.82 | 109/39 | 1.92 | 1.13–3.25 |
15+ | 37/154 | 0.82 | 0.51–1.34 | 101/154 | 1.26 | 0.86–1.83 | 101/37 | 1.68 | 0.97–2.92 |
Heterogeneity between groups within current smokers | P=0.8 | P=0.8 | P=0.9 | ||||||
