Figure 4
From: c-Myc alters the DNA damage-induced G2/M arrest in human mammary epithelial cells
c-Myc-overexpressing cells are sensitive to DNA damage-induced apoptosis. DNA damage eventually induces apoptosis of c-Myc-overexpressing cells. (A) A time-course change in the percentage of apoptotic cells was measured with Hoechst 33258 and cleaved PARP staining. (B) Representative figures, showing apoptotic cells with fragmented DNA, in Hoechst 33258 staining and with cleaved PARP.
