Figure 2
From: Phase II trial of intralesional therapy with interleukin-2 in soft-tissue melanoma metastases
Immunoflourescence staining for Melan A/Mart-1 (green) and caspase-3 (red) detects vital and apoptotic tumour cells. Nuclei stained blue. Images were taken using a CLSM at 630-fold magnification (A). Confocal laser scanning microscopy image of the inflammatory infiltrate: CD3-positive T-lymphocytes stained blue, CD56-positive/CD3-negative NK cells stained red, nuclei green, final magnification 630-fold (B). Most NK cells are found in small groups near to a capillary (arrow).
