Table 10 Published rates of female infertility after treatment of GCTs
Study | Total cases | Assessable cases who had chemo | Percent dysgerminomas | Chemotherapy | Number who wished children | Fertile patients | Number who were infertile (%) |
|---|---|---|---|---|---|---|---|
Pektasides (Pektasides et al, 1987) | 40 | 17 | 0% | POMB/ACE | 6 | 5 | 1 (17%) |
Gershenson (Gershenson, 1988) | 40 | 40 | N/Ab | Various | 16 | 11 | 5 (31%) |
Huang (Huang, 1990) | 28 | 26 | 8% | N/A | 10 | 7 | 3 (30%) |
Wu (Wu et al, 1991) | 28 | 22 | 7% | Various | 10 | 7 | 3 (30%) |
Long (Long et al, 1993) | 15 | 15 | N/A | N/A | N/A | 4 | N/A |
Mitchell (Mitchell et al, 1999) | 69 | 26 | 0% | Various | N/A | 11 | N/A |
Brewer (Brewer et al, 1999) | 26 | 16 | 100% | BEPa | 5 | 3 | 2 (40%) |
Perrin (Perrin et al, 1999) | 45 | 29 | 51% | Various | 9 | 7 | 2 (22%) |
Low (Low et al, 2000) | 91 | 39 | 42% | Various | 20 | 19 | 1 (5%) |
Kanazawa (Kanazawa et al, 2000) | 31 | 18 | 23% | Various | 9 | 8 | 1 (11%) |
Zanetta (Zanetta et al, 2001) | 169 | 73 | 41% | Various | 20 | 16 | 4 (20%) |
Tangir (Tangir et al, 2003) | 106 | 64 | N/A | Various | 38 | 29 | 9 (24%) |
This study | 71 | 35 | 10% | POMB/ACE | 28 | 21 | 7 (25%) |
a PEB/BEP=Cisplatin, etoposide, and bleomycin. | |||||||
b N/A=data not available from published article. | |||||||
