Table 3 Male infertility rates by stage and treatment

From: Infertility rates following POMB/ACE chemotherapy for male and female germ cell tumours – a retrospective long-term follow-up study

Patient characteristic

% infertile (proportion of total−fertile+infertile)

P- value

Stage at diagnosis

  

 I

27% (3/11)

 

 II

28% (7/25)

 

 III or IV

33% (8/24)

P=0.93

 Unknown

0% (0/4)

 

Given radiotherapy

100% (6/6)

P<0.0001

No radiotherapy

21% (12/58)

 

Had a laparotomy/RPLND

43% (6/14)

P=0.19

No laparotomy

24% (12/50)

 

Including all causes of infertility

  

 <400 mg m−2 cisplatin

26% (12/46)

 

 >400 mg m−2 cisplatin

29% (5/17)

P=0.72

Excluding nonchemotherapy causes of infertility

  

 <400 mg m−2 cisplatin

13% (5/39)

 

 >400 mg m−2 cisplatin

21% (3/14)

P=0.42

P-values determined by Fisher's exact or χ2 tests.