Table 7 Comparison of the mean cisplatin and cyclophosphamide doses given to women with GCTs who were subsequently found to be fertile or infertile

From: Infertility rates following POMB/ACE chemotherapy for male and female germ cell tumours – a retrospective long-term follow-up study

 

Fertile

Infertile

P -value (95% CI)

Mean dose of cisplatin

380.9a mg m−2 (n=20)

424.3a mg m−2 (n=6)

P=0.65 (–102.6 to 65.0 mg/m2)

Mean dose of cyclophosphamide

1625 mg m−2 (n=20)

1714 mg m−2 (n=6)

NS

a One patient who received carboplatin instead of cisplatin was excluded in each group.

P-value determined by t-test.

NS=nonsignificant.