Table 9 Published rates of male infertility after treatment for GCTs

From: Infertility rates following POMB/ACE chemotherapy for male and female germ cell tumours – a retrospective long-term follow-up study

Study

Total cases

Assessable cases who had chemo

Percent seminomas

Chemotherapy

Number who wished children

Fertile patients

Number who were infertile (%)

Roth (Roth et al, 1988)

229

147

6

PVB±Ab

N/A

24

N/Ac

Hansen (Hansen et al, 1990)

177

28

49

Various

8

3

5 (63%)

Bisset (Bissett et al, 1990)

120

74

11

Various

N/A

18

N/A

Pont (Pont et al, 1996)

42

25

0

2 PEBa

N/A

7

N/A

Hartman (Hartmann et al, 1999)

124

98

20

Various

40

21

19 (48%)

Petersen (Petersen and Hansen, 1999)

22

22

0

PVB

16

9

7 (44%)

Bohlen (Bohlen et al, 2001)

59

49

0

PVB or BEP

N/A

16

5

This study

366

153

0

POMB-ACE

64

46

18 (28%)

a PEB/BEP=cisplatin, etoposide, and bleomycin.

b PVB±A=cisplatin, vincristine, and bleomycin with or without adriamycin.

c N/A=data not available from published article.

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