Table 1 Correlation analyses of cell cycle regulators and clinicopathological parameters in 92 cases of DCIS

From: Tissue microarray analyses of G1/S-regulatory proteins in ductal carcinoma in situ of the breast indicate that low cyclin D1 is associated with local recurrence

 

Cyclin D1

Cyclin E

p16

p27

Cyclin D1

—

0.257/0.119

0.0001/0.382***

0.0001/0.373***

Cyclin E

—

—

0.157/0.149

0.769/0.031

p16

—

—

—

0.039/0.215*

Ki-67

0.079/0.206

0.046/0.233*

0.545/0.071

0.451/−0.089

Age

0.486/0.074

0.592/0.057

0.784/0.029

0.048/−0.207*

OR+/−

0.114/0.203

0.312/−0.131

0.983/−0.013

0.381/0.113

PR+/−

0.171/0.147

0.098/−0.177

0.315/−0.108

0.8860/0.016

Nuclear grade

0.882/0.024

0.497/0.072

0.790/−0.028

0.886/0.016

Growth pattern

0.555/0.062

0.508/0.070

0.122/0.162

0.748/0.034

(P-value/r-value). *P<0.05, ***P<0.001. Progesteron receptor (PR).

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