Table 3 Stage 1 grade of haematological toxicity

From: A phase I (tumour site-specific) study of carboplatin and temozolomide in patients with advanced melanoma

 

0

1

2

 

Cycles (patients)

Carboplatin AUC 3

 Anaemia

6 (3)

2(1)

2 (1)

 Thrombocytopenia

10 (3)

0(0)

0 (0)

 Neutropenia

9 (3)

1(1)

0 (0)

Carboplatin AUC 4

 Anaemia

4 (3)

6 (3)

1 (1)

 Thrombocytopenia

4 (3)

6 (3)

1 (2)

 Neutropenia

6 (3)

5 (3)

0 (0)

Carboplatin AUC 5

 Anaemia

5 (3)

2 (2)

0 (0)

 Thrombocytopenia

5 (3)

2 (1)

0 (0)

 Neutropenia

5 (3)

2 (1)

0 (0)

Carboplatin AUC 6

 Anaemia

4 (2)

0 (0)

1 (1)

 Thrombocytopenia

4 (3)

1 (1)

0 (0)

 Neutropenia

4 (3)

1 (1)

0 (0)

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