Table 4 Univariate and multivariate stepwise Cox model analysis of survival for all patients

From: Subcutaneous interleukin-2, interferon alpha-2b and 5-fluorouracil in metastatic renal cell carcinoma as second-line treatment after failure of previous immunotherapy: a phase II trial

 

Univariate

Multivariate

Prognostic factor

P

HR

95% CI

P

Objective response and stabilisation to second–line immunotherapy with IL-2, IFNα and 5-FU

0.006

2.43

1.05–5.6

0.038

General performance status (Karnofsky ⩾90 vs <90%)

0.007

3.72

1.55–8.91

0.003

Time interval from primary tumour to occurrence of metastases (⩽12 vs >12 months)

0.07

2.71

1.08–6.78

0.033

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