Table 2 Association of the 1100delC and I157T variants of the CHEK2 gene with patients with unselected prostate cancer or HPC
From: CHEK2 variants associate with hereditary prostate cancer
Mutation and sample | No. of carriers/total (frequency) | OR | 95% CI | P |
|---|---|---|---|---|
1100delC | ||||
Controls | 2/480 (0.4%) | 1.00 | ||
Patients with unselected Prostate cancer | 7/537 (1.3%) | 3.14 | 0.65−15.16 | 0.15 |
Patients with HPC | 4/120 (3.3%) | 8.24 | 1.49−45.54 | 0.02a |
I157T | ||||
Controls | 26/480 (5.4%) | 1.00 | ||
Patients with unselected Prostate cancer | 42/537 (7.8%) | 1.48 | 0.89−2.46 | 0.13 |
Patients with HPC | 13/120 (10.8%) | 2.12 | 1.06−4.27 | 0.04a |
a Statistically significant. | ||||
